Saitama from One Punch Man is widely recognized as the strongest character in his universe, with his signature ability allowing him to eliminate any opponent with a single punch.
His immense power was further highlighted in chapter 168 of the manga, where he unleashed a sneeze so powerful that it nearly obliterated Jupiter.
Alucard’s immortality could make him a true nightmare for Saitama (Photo: One Punch Man/Madhouse)Even though defeating Saitama is an extraordinary challenge, that doesn’t mean there aren’t individuals who could stand their ground against him.
14. Anti-Spiral (Tengen Toppa Gurren Lagann)
Anti-Spiral, a cosmic entity from Tengen Toppa Gurren Lagann, wields powers beyond comprehension, with no known limitations to their abilities.
Since they operate on a universal scale, threats confined to a single planet hold no meaning to them. Saitama, while undeniably strong and capable of planetary destruction, would be powerless against a being regarded as godlike by many.
13. Alucard (Hellsing)
Alucard, a fearsome and battle-hardened warrior, possesses a vast array of abilities that make him a formidable adversary for Saitama. His expertise in black magic, along with his exceptional swordsmanship, enhances his combat prowess.
What truly sets him apart is his near-invulnerability. Unlike most beings, Alucard’s body isn’t composed of flesh and bone but rather a fusion of shadows and stolen souls. As a result, physical attacks have little effect on him, and any damage sustained can be rapidly regenerated.
Additionally, Alucard has the power to absorb the abilities of others by consuming their blood. If he were to bite Saitama, he could transform into an unstoppable One-Punch Vampire.
12. Nanika (Hunter x Hunter)
Nanika, an enigmatic entity from the Dark Continent in Hunter x Hunter, inhabits the body of Alluka, the second-youngest member of the Zoldyck family. Her abilities defy limitations, posing a threat to even the most powerful beings.
Instead of relying on physical combat, Nanika’s wishes carry immeasurable influence. One instance demonstrated her ability to heal injuries deemed impossible to recover from, as seen when she restored Gon after he sacrificed all his Nen.
If someone were to request Nanika to eliminate Saitama, her powers could likely make it a reality.
11. Goku (Mastered Ultra Instinct) (Dragon Ball Super)
Saitama might have the upper hand initially in a fight against Goku, but the dynamic changes drastically once the Saiyan reaches his Mastered Ultra Instinct state.
This transformation allows Goku to react and power up instinctively, making it nearly impossible for Saitama to land a meaningful hit. Mastered Ultra Instinct gave Goku the advantage over Jiren, who was regarded as one of the strongest beings in the universe, and it also places him above certain deities in terms of power.
10. Tokisaki Kurumi (Date A Live)
Despite Saitama’s overwhelming physical strength, he would struggle against an opponent whose abilities revolve around manipulating time itself.
Nanika’s wish-based power might bypass even Saitama’s limitless strength (Photo: One Punch Man/Madhouse)Kurumi, a spirit feared in the Date A Live universe, nearly brought humanity to the brink of extinction using her mastery over time. Beyond time manipulation, she has the capability to generate multiple clones of herself.
With her ability to create an army of identical versions, Saitama could find himself overwhelmed in battle.
9. Ryuk (Death Note)
Ryuk, a Shinigami from Death Note, is an immortal being beyond the reach of any conventional attack. As a god of death, he exists on an entirely different plane, rendering him untouchable by Saitama’s punches.
The only humans capable of seeing him are those who possess a Death Note, which Saitama does not. Ryuk wouldn’t even need to engage in a fight—writing Saitama’s name in his notebook would be enough to ensure his demise.
8. Madara Uchiha (Naruto)
Renowned as the most powerful Uchiha, Madara’s immense strength was evident even in his early years. As he grew, he honed his skills to near invincibility, overpowering legendary warriors with ease.
While both Madara and Saitama are nearly unbeatable in direct combat, Madara possesses a time-reversal technique that could alter the course of battle. By leveraging this ability, he could create an opportunity to bring Saitama down.
7. Rimuru Tempest (That Time I Got Reincarnated as a Slime)
Rimuru Tempest is a master of magic with an extraordinary skill set that includes the ability to halt time.
In a head-to-head fight, Saitama might dominate with sheer physical strength, but if Rimuru were to use her time-freezing ability, she could neutralize him effortlessly. Her rapid healing ability ensures that any damage sustained from Saitama’s attacks would be rendered meaningless.
6. Baraggan Louisenbairn (Bleach)
Baraggan Louisenbairn possesses multiple abilities that could give him an advantage over Saitama. One of his most powerful techniques involves slowing down time, which directly affects the movements of his opponents, making them more vulnerable.
Additionally, his unique power allows him to accelerate the aging process of those he touches. If he were to make contact with Saitama, he could rapidly age him, stripping him of his strength over time.
5. Gojo Satoru (Jujutsu Kaisen)
Gojo’s Infinity ability played a crucial role when he trapped a volcanic curse, preventing it from moving. The same power could be used to render Saitama immobile in battle.
His Domain Expansion technique also traps opponents in a space where they experience infinite knowledge, paralyzing them mentally and physically. Gojo’s Infinity creates a barrier that prevents direct contact, meaning Saitama’s punches would be unable to reach him.
4. Demon Form Tanjiro (Demon Slayer)
While Tanjiro in his human state would struggle against Saitama, his demon transformation changes the equation entirely.
Tokisaki Kurumi’s time manipulation could create an endless battle (Photo: One Punch Man/Madhouse)His regenerative abilities allow him to recover from severe injuries, making it difficult for Saitama’s attacks to have any lasting impact. Additionally, his ability to generate electric shockwaves with his voice could send Saitama flying before he even gets the chance to strike.
While Saitama excels in fighting human opponents, supernatural beings present a completely different challenge.
3. Saiki Kusuo (The Disastrous Life of Saiki K.)
Saiki Kusuo’s psychic abilities make him a near-unbeatable adversary. Even with Saitama’s godlike strength, he would find it impossible to counter Saiki’s vast range of supernatural skills.
From teleportation and mind manipulation to turning people into stone with his gaze, Saiki has an arsenal of techniques that could neutralize Saitama without the need for direct combat.
2. Zeno (Dragon Ball)
Zeno, the supreme deity of Dragon Ball, holds the ability to erase entire universes with a mere gesture.
Fighting him would be meaningless, as he doesn’t rely on physical strength. If Saitama were to face Zeno, he would be erased from existence before even having the chance to throw a punch.
Beyond that, Zeno can mimic the abilities of others. Even if he decided to engage in combat rather than erasing Saitama outright, he could simply replicate his powers and use them against him.
1. Anos Voldigoad (The Misfit of Demon King Academy)
Anos Voldigoad, known as the Demon King of Tyranny, is regarded as one of the most powerful beings in anime history. His regenerative abilities allow him to recover from even the most severe injuries, ensuring that Saitama’s attacks would have little effect.
With the power to obliterate his enemies using the destructive force in his eyes, Anos wouldn’t even need to engage in hand-to-hand combat. If necessary, his magical gaze could put Saitama to sleep, granting him the perfect opportunity to finish the fight.